n. refers to a class of non-benzodiazepine anxiolytics for which the prototype is buspirone. These drugs relieve anxiety by acting as partial agonists at the 5-HT 4 serotonin receptor (see serotonin-receptor agonists). Other drugs in this class include gepirone, tandospirone, and ipsapirone. Azaspirones produce less sedation than the traditional benzodiazepines and they lack the abuse potential. However, their onset of action is approximately 2-3 weeks, and therefore, they cannot be used to manage acute or paroxysmal anxiety. Also known as azaspirodecanediones.

AZASPIRONES: “Azaspirones are a slower acting pharmaceutical drug that are commonly used in the treatment of anxious symptoms.”
Scroll to Top