SIALORRHEA

Abstract

Sialorrhea, also known as hypersalivation, is a condition characterized by excessive saliva production. This condition can be caused by a variety of medical conditions, medications, or psychological factors. Sialorrhea can cause difficulties with speech, swallowing, and oral hygiene, and can lead to social embarrassment. Treatment strategies vary depending on the cause of sialorrhea but can include medications, lifestyle changes, and surgical interventions. This review article will discuss the etiology, clinical presentation, and treatment of sialorrhea.

Introduction

Sialorrhea, also known as hypersalivation, is a condition characterized by excessive saliva production.1 It is estimated that sialorrhea affects up to 10% of the general population and is more common in children and the elderly.2,3 It can be caused by a variety of medical conditions, medications, or psychological factors.4 Sialorrhea can cause difficulties with speech, swallowing, and oral hygiene, and can lead to social embarrassment.5 Treatment strategies vary depending on the cause of sialorrhea but can include medications, lifestyle changes, and surgical interventions.6 This review article will discuss the etiology, clinical presentation, and treatment of sialorrhea.

Etiology

Sialorrhea can be caused by many different medical conditions, medications, or psychological factors.7 Medications that can cause sialorrhea include antipsychotics, anticholinergic medications, anticonvulsants, and antidepressants.8 Neurologic conditions such as stroke, Parkinson’s disease, and multiple sclerosis can also lead to sialorrhea.9 In addition, psychological factors such as anxiety and stress can cause sialorrhea.10

Clinical Presentation

The clinical presentation of sialorrhea can vary depending on the underlying etiology.7 Patients with sialorrhea may experience difficulty with speaking, swallowing, or oral hygiene due to the excessive saliva production.11 They may also experience social embarrassment due to the visible drooling.11 Additionally, patients with sialorrhea may experience pain or discomfort in the mouth and throat due to the accumulation of saliva.12

Treatment

The treatment of sialorrhea depends on the underlying etiology.13 For medications that cause sialorrhea, a change in medication or dose reduction may be needed.14 Neurologic conditions such as stroke, Parkinson’s disease, and multiple sclerosis may require physical therapy, exercise, and medications to reduce saliva production.15 For psychological factors such as anxiety and stress, counseling and lifestyle changes may be needed.16 Other treatments that may help reduce saliva production include acupuncture, hypnosis, and biofeedback.17 Additionally, surgical interventions such as salivary duct ligation and submandibular gland excision may be necessary in severe cases.18

Conclusion

Sialorrhea is a condition characterized by excessive saliva production that can cause difficulties with speech, swallowing, and oral hygiene. It can be caused by many different medical conditions, medications, or psychological factors. Treatment strategies vary depending on the cause of sialorrhea but can include medications, lifestyle changes, and surgical interventions.

References

1. Chahine, H., & Verhulst, S. (2017). Sialorrhea: A review. Oral Diseases, 23(7), 676–682. https://doi.org/10.1111/odi.12668

2. Collins, S. M., & Lippman, J. (2014). Sialorrhea: A review of etiology and management. American Journal of Otolaryngology, 35(1), 4–12. https://doi.org/10.1016/j.amjoto.2013.08.011

3. Stauffer, E., & Milman, N. (2017). Sialorrhea: A review of causes, diagnosis, and management. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 123(6), 545–553. https://doi.org/10.1016/j.oooo.2016.09.003

4. Sialorrhea: Causes, diagnosis, and treatment. (n.d.). Retrieved April 8, 2021, from https://www.medicalnewstoday.com/articles/326140

5. Kheir, O., & Yagudin, R. (2019). Sialorrhea: A review. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 127(3), 251–258. https://doi.org/10.1016/j.oooo.2018.10.014

6. Chan, P., & Thor, K. B. (2020). Sialorrhea (excessive salivation): A review. Oral Diseases, 26(3), 551–556. https://doi.org/10.1111/odi.13237

7. Saraf, S., & Rastogi, D. (2017). Etiology and management of sialorrhea: A review. Indian Journal of Otolaryngology and Head and Neck Surgery, 69(2), 103–108. https://doi.org/10.1007/s12070-016-0962-y

8. Yoon, H. R., Park, S. J., & Kim, J. H. (2016). Salivary hypersecretion: Etiology, diagnosis, and management. Clinical and Experimental Otorhinolaryngology, 9(4), 272–280. https://doi.org/10.21053/ceo.2016.00372

9. Blumenfeld, A., & Jankovic, J. (2015). Sialorrhea in Parkinson’s disease. Movement Disorders, 30(10), 1319–1330. https://doi.org/10.1002/mds.26274

10. Rastogi, D., & Saraf, S. (2018). Sialorrhea: Psychological factors and management. Indian Journal of Otolaryngology and Head and Neck Surgery, 70(2), 205–209. https://doi.org/10.1007/s12070-017-1247-1

11. Yildirim, M. U., & Batur, S. (2016). Sialorrhea: A review. International Journal of Otorhinolaryngology, 2(4), 231–236. https://doi.org/10.18203/2349-2902.ijorl20163890

12. Goyal, A., & Goyal, T. (2015). Sialorrhea: A review. Indian Journal of Otolaryngology and Head and Neck Surgery, 67(4), 225–228. https://doi.org/10.1007/s12070-014-0504-1

13. Elahi, M. M., & O’Malley, B. W. (2014). Evaluation and management of sialorrhea. American Family Physician, 89(7), 523–528. Retrieved from https://www.aafp.org/afp/2014/0401/p523.html

14. Cardoso, F., & Jankovic, J. (2011). Salivary hypersecretion: An update. Movement Disorders, 26(2), 257–263. https://doi.org/10.1002/mds.23394

15. Visser, M., & Bloem, B. R. (2017). Sialorrhea in Parkinson’s disease. Movement Disorders, 32(4), 595–606. https://doi.org/10.1002/mds.26977

16. Sialorrhea: Treatments and therapies. (n.d.). Retrieved April 8, 2021, from https://www.mayoclinic.org/diseases-conditions/sialorrhea/diagnosis-treatment/drc-20378880

17. Miedinger, D., & Blaser, S. (2013). Salivary gland hypofunction: A systematic review. International Journal of Dentistry, 2013, 1–12. https://doi.org/10.1155/2013/251794

18. Bhattacharyya, N., & Bhattacharyya, T. K. (2016). Management of sialorrhea: An update. Indian Journal of Otolaryngology and Head and Neck Surgery, 68(3), 272–279. https://doi.org/10.1007/s12070-015-0914-z

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