Tag: Anticholinergic Effects

November 21, 2025 / Mohammed looti

ANTICHOLINERGIC EFFECTS

Introduction to Anticholinergic Effects The term anticholinergic effects refers broadly to the physiological and psychological outcomes—encompassing both intended therapeutic benefits and unintended adverse reactions—that result from the inhibition of acetylcholine (ACh) signaling within the nervous system. Specifically, these effects arise when a medication or substance acts as an antagonist, blocking the action of ACh at […]

November 16, 2025 / Mohammed looti

PERIPHERAL ANTICHOLINERGIC SYNDROME

Introduction and Definition The Peripheral Anticholinergic Syndrome (PACS) is a recognized clinical entity arising from the excessive and often additive blockade of muscarinic acetylcholine receptors located within the peripheral nervous system. This syndrome is particularly prevalent in clinical settings where patients are receiving complex regimens involving multiple psychopharmacological agents, a practice known as polypharmacy. The […]