Tag: central sensitization

November 30, 2025 / Mohammed looti

PERCEPTUAL SENSITIZATION

Introduction to Perceptual Sensitization Perceptual sensitization refers to a fundamental neurophysiological and psychological process characterized by an increased responsiveness of the sensory system to stimuli over time. Unlike sensory adaptation or habituation, which involve a decrease in response intensity following repeated exposure, sensitization leads to a heightened state where a previously innocuous or mild stimulus […]

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November 13, 2025 / Mohammed looti

SPINAL GATE

Introduction to the Spinal Gate Mechanism The concept of the Spinal Gate, frequently referenced as the gating mechanism, is foundational to understanding the neurophysiology of pain perception and modulation within the central nervous system. This mechanism is an active, regulatory filter situated strategically within the dorsal horn of the spinal cord, primarily involving the intricate […]

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