KOCHER-DEBRE-SEMELAIGNE SYNDROME
Definition and Overview of Kocher-Debre-Semelaigne Syndrome The Kocher-Debre-Semelaigne Syndrome (KDS), often categorized as a rare manifestation of severe pediatric hypothyroidism, is a distinct clinical entity primarily affecting infants and young children. This disorder is critically defined by a specific myopathy characterized paradoxically by both generalized muscle weakness and marked muscular pseudohypertrophy, leading to a misleadingly […]