Tag: crohn’s disease

February 18, 2026 / Mohammed looti

SANDIMMUNE

An Introduction to Sandimmune and Its Pharmacological Evolution Sandimmune, a brand name for the generic drug cyclosporine, stands as a cornerstone in the field of modern immunopharmacology. Originally discovered in the 1970s as a metabolite produced by the soil fungus Tolypocladium inflatum, this potent immunosuppressant revolutionized the success rates of solid organ transplantations. Before its […]

December 6, 2025 / Mohammed looti

COLITIS

Abstract This extensive entry provides a comprehensive overview of colitis, defining it as a general term for inflammation affecting the large intestine, or colon. We examine the condition’s historical recognition, tracing its nomenclature back to the late 19th century. Furthermore, this article delves into the diverse etiologies of colitis, distinguishing between infectious, autoimmune, ischemic, and […]