Cornelia de Lange Syndrome: Understanding Genetic Origins
Historical Context and Nomenclature The condition historically referred to as Amsterdam Dwarf Disease, or sometimes designated as the Amsterdam type of retardation, is recognized in contemporary medicine primarily as Cornelia de Lange Syndrome (CdLS). This complex, multisystem developmental disorder was first comprehensively described in 1933 by the Dutch pediatrician Cornelia de Lange, following her detailed […]