Tag: leptin

February 10, 2026 / Mohammed looti

LEPTIN

The Fundamental Nature and Physiological Significance of Leptin Leptin is a critical peptide hormone, primarily synthesized and secreted by adipocytes, or fat cells, which serves as a foundational element in the complex architecture of human physiology. Since its discovery, it has ascended to the status of one of the most rigorously investigated hormones within the […]

December 25, 2025 / Mohammed looti

LIPOSTATIC HYPOTHESIS

Introduction to the Lipostatic Hypothesis The lipostatic hypothesis is a fundamental physiological model developed by Dr. Jules Hirsch in 1965, proposing that the body actively regulates its fat stores to maintain a constant, predetermined level known as a set-point. This hypothesis characterizes adipose tissue not merely as a passive storage site for excess calories, but […]