Tag: ligand-gated ion channel

November 24, 2025 / Mohammed looti

KAINATE RECEPTOR

Introduction and Definition Kainate Receptors (KARs) constitute one of the three main classes of ionotropic glutamate receptors, alongside AMPA and NMDA receptors, playing fundamental roles in excitatory neurotransmission within the central nervous system (CNS). These receptors derive their name from their high affinity for the specific exogenous agonist, kainic acid, a powerful neurotoxin derived from […]

November 24, 2025 / Mohammed looti

LIGAND-GATED ION CHANNEL

Introduction to Ligand-Gated Ion Channels Ligand-gated ion channels (LGICs), often referred to as ionotropic receptors, constitute a fundamental class of transmembrane proteins crucial for rapid signaling across biological membranes, particularly within the nervous system. These channels are defined by their ability to selectively permit the passage of specific ions—such as sodium (Na+), potassium (K+), chloride […]