Tag: local excitatory state


LOCAL EXCITATORY STATE (LES)

Introduction to the Local Excitatory State (LES) The Local Excitatory State (LES) represents a fundamental concept in neurophysiology, describing a localized, temporary, yet sustained elevation in the intrinsic excitability of specific neuronal populations within the central nervous system. This phenomenon moves beyond simple transient synaptic transmission, suggesting a robust alteration in the neuron’s readiness to […]

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