Tag: neuroleptics

February 17, 2026 / Mohammed looti

RISPERIDONE

Pharmacological Classification and Mechanism of Action Risperidone is a potent second-generation antipsychotic (SGA), commonly referred to as an atypical antipsychotic, belonging to the benzisoxazole derivative class. Unlike first-generation antipsychotics which primarily target dopamine D2 receptors, risperidone is characterized by its high affinity for both serotonin 5-HT2A and dopamine D2 receptors. This dual-antagonism is central to […]

November 11, 2025 / Mohammed looti

PHENOTHIAZINES

Introduction to Phenothiazines The phenothiazines represent a critical class of chemically analogous compounds, predominantly recognized for their extensive utility as antipsychotic drugs within the field of psychopharmacology. The initial development and subsequent therapeutic application of these agents marked a watershed moment in the treatment of severe mental illnesses, particularly schizophrenia. Cultivated initially in the 1950s, […]