PELIZAEUS-MERZBACHER DISEASE
Definition and Overview Pelizaeus-Merzbacher Disease (PMD) is a rare, progressively debilitating X-linked leukodystrophy affecting the central nervous system (CNS). It is classified as an uncommon, progressive degenerative disorder characterized fundamentally by a failure in the formation and maintenance of myelin, the fatty sheath vital for insulating nerve fibers and ensuring rapid signal transmission. The core […]