Tag: phenothiazine antipsychotics

November 7, 2025 / Mohammed looti

ALIPHATIC PHENOTHIAZINES

Introduction to Aliphatic Phenothiazines The class of compounds known as aliphatic phenothiazines represents a foundational group within the broader spectrum of antipsychotic medications, characterized fundamentally by the presence of an aliphatic side chain attached to the nitrogen atom at position 10 of the phenothiazine nucleus. This specific structural characteristic distinguishes them chemically and pharmacologically from […]

November 1, 2025 / Mohammed looti

TUBEROINFUNDIBULAR TRACT

Introduction and Definitional Framework The tuberoinfundibular tract (TIDA) represents one of the three primary neural pathways within the central nervous system that relies fundamentally upon dopamine (DA) as its primary neurotransmitter. This tract is distinct from the other major dopaminergic systems, namely the nigrostriatal and mesolimbic/mesocortical pathways, due to its highly localized function and unique […]