Allosteric Modulation: Tuning Your Brain’s Chemistry
Defining Allosteric Modulation Allosteric modulation refers to the process by which a chemical entity, known as an allosteric modulator, binds to a site on a macromolecular receptor complex that is physically distinct from the primary, or orthosteric binding site, where the endogenous ligand or primary neurotransmitter typically binds. This binding event does not directly activate […]