Tag: SRY gene

December 5, 2025 / Mohammed looti

Y CHROMOSOME

Introduction to the Y Chromosome The Y Chromosome, often recognized as the defining genetic element for male sex, is one of the two sex chromosomes found in humans and other placental mammals. Paired with the X chromosome, it forms the heteromorphic XY sex determination system. Its central biological significance lies in carrying the crucial gene […]

October 11, 2025 / Mohammed looti

SEX REVERSAL ON Y (SRY)

The Role of SRY in Disorders of Sex Development Core Definition and Genetic Mechanism The Sex-determining Region on the Y chromosome, universally abbreviated as SRY gene, represents the pivotal genetic factor responsible for initiating male sex determination in humans and most other placental mammals. This gene is exclusively located on the short arm of the […]