Tag: Substance P

December 3, 2025 / Mohammed looti

NEUROKININ

Introduction and Definition of Neurokinins Neurokinins represent a crucial and highly complex family of neuropeptides that function as potent neurotransmitters and neuromodulators within the mammalian nervous system. They are classified biochemically as members of the larger tachykinin family, unified by a common C-terminal amino acid sequence (Phe-X-Gly-Leu-Met-NH2), which is essential for binding to their specific […]

November 29, 2025 / Mohammed looti

SUBSTANCE P

Introduction to Substance P Substance P (SP) is a foundational neurochemical classified as an undecapeptide, meaning it consists of eleven amino acid residues. It belongs to the tachykinin family of peptides, a group characterized by a conserved C-terminal sequence, which is essential for binding to its primary receptor. This potent molecule functions critically as both […]