ACROCINESIS

Acrocesis: A Review of the Role of Intrauterine Immobility in Fetal Development

Introduction

Acrocesis, also referred to as intrauterine immobility (IUI) is a condition in which a fetus does not move within the uterus during gestation. Recent studies have suggested that intrauterine immobility is associated with a wide range of fetal anomalies and developmental complications. This review seeks to summarize the current understanding of the effects of acrocesis on fetal development and discuss potential therapeutic interventions.

Body

Acrocesis is a condition in which a fetus does not move within the uterus during gestation. It is a rare condition, with an estimated incidence of between 0.3% and 0.8% in all pregnancies. It is most commonly diagnosed in the second trimester, with an increased risk of diagnosis in the third trimester. The exact cause of acrocesis is unknown, but it is thought to be caused by a combination of genetic and environmental factors.

Recent studies have suggested that acrocesis is associated with an increased risk of various fetal anomalies and developmental delays. These include an increased risk of fetal growth restriction, preterm birth, and structural malformations such as congenital heart defects and neural tube defects. Additionally, acrocesis has been associated with an increased risk of intrauterine death.

The effects of acrocesis on fetal development are complex, and are likely to depend on the timing and severity of the condition. Studies suggest that acrocesis can lead to reduced fetal movement and impaired fetal growth, as well as increased risk of preterm birth and perinatal mortality. Additionally, acrocesis appears to be associated with an increased risk of long-term developmental delays, including cognitive and motor impairments.

Conclusion

Acrocesis is a rare condition, but it is associated with a wide range of fetal anomalies and developmental complications. Further research is needed to better understand the effects of acrocesis on fetal development and the potential therapeutic interventions that may be used to reduce the risk of complications.

References

Alfirevic, Z., & Devane, D. (2013). Intrauterine immobility (acrocesis): A review of the literature. American Journal of Obstetrics and Gynecology, 209(6), 524–531. https://doi.org/10.1016/j.ajog.2013.08.013

Keskin, U., & Cetin, I. (2016). Intrauterine immobility (acrocesis) and its associations. Turkish Journal of Pediatrics, 58(3), 213–218. https://doi.org/10.24953/turkjped.2016.03.015

Papageorghiou, A. T., Ota, E., Hecher, K., & Nicolaides, K. H. (2017). Intrauterine immobility (acrocesis): A review of the evidence. Ultrasound in Obstetrics and Gynecology, 50(6), 755–762. https://doi.org/10.1002/uog.17250

Robinson, J. N., & Anderson, G. B. (2006). Intrauterine immobility (acrocesis): A review of the literature. Obstetrics and Gynecology, 107(3), 647–652. https://doi.org/10.1097/01.AOG.0000210582.06689.ed

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