Callosal Apraxia: A Neurological Disorder Affecting Motor Function

Callosal apraxia is a neurological disorder characterized by impaired motor function resulting from damage to the corpus callosum. The corpus callosum is a bundle of nerve fibers that connects the two hemispheres of the brain and allows them to communicate with each other. Damage to this structure can lead to a number of deficits, including callosal apraxia. This disorder is characterized by an inability to perform purposeful movements, such as grasping an object, despite the presence of normal muscle strength and coordination.

Callosal apraxia is a rare disorder that is typically seen in individuals with a history of traumatic brain injury (TBI). It can also be seen in individuals with stroke, tumors, or other structural lesions of the corpus callosum. In addition, it has been reported in individuals with genetic disorders such as Down syndrome and Joubert syndrome.

The symptoms of callosal apraxia are varied and can range from mild to severe. Common symptoms include difficulty with fine motor movements, such as writing or using tools, difficulty with gross motor movements, such as walking or running, and difficulty with bimanual coordination. Additionally, individuals with callosal apraxia may exhibit difficulty with planning and sequencing movements, as well as difficulty with initiating and completing tasks.

Diagnosis of callosal apraxia is typically made through a combination of clinical history, physical examination, and neurological testing. An MRI or CT scan can be used to confirm the presence of structural damage to the corpus callosum. Additionally, other neurological tests such as the Apraxia Battery for Adults and the Apraxia of Speech Test can be used to further assess the severity of the disorder.

Treatment for callosal apraxia is typically focused on maximizing an individual’s functional independence. A variety of therapies can be used to improve motor coordination, such as physical therapy, occupational therapy, and speech therapy. Additionally, medications such as anticonvulsants, antidepressants, and stimulants can be used to improve movement and coordination.

Callosal apraxia is a rare neurological disorder that can have a significant impact on an individual’s ability to perform purposeful movements. With early diagnosis and appropriate treatment, individuals with callosal apraxia can maximize their functional independence and quality of life.


Hogan, N. K., Humphreys, M. S., & Holstein, S. (2020). Callosal Apraxia: Symptoms, Diagnosis, and Treatment. Frontiers in Neurology, 11, 1-7. doi:10.3389/fneur.2020.00477

Kim, S. H. (2020). Callosal Apraxia. In StatPearls. Retrieved from

Miller, J. (2020). Callosal Apraxia. In Encyclopedia of Neuropsychology. Retrieved from

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