Deep depression is a serious mental disorder that has a significant impact on a person’s ability to function. It is characterized by persistent low mood and lack of interest in life, as well as feelings of worthlessness, guilt, and helplessness. Deep depression can lead to a range of both physical and psychological symptoms, including fatigue, changes in sleep and appetite, difficulty concentrating, and even thoughts of suicide. It can have a profound impact on an individual’s quality of life and their ability to function in daily life.

The exact cause of deep depression is not known, but it is thought to be the result of a combination of biological, psychological, and environmental factors. Biological factors may include genetic predisposition, certain hormones, or changes in neurotransmitters in the brain. Psychological factors may include traumatic life events, personality traits, or family dynamics. Environmental factors may include social isolation, financial stress, or work-related stress.

In order to diagnose and treat deep depression, a thorough assessment of the individual’s history, current symptoms, and other factors is necessary. Treatment may include medication, psychotherapy, or a combination of the two. Medication may include antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), or mood stabilizers, such as lithium. Psychotherapy may involve cognitive-behavioral therapy (CBT), interpersonal therapy (IPT), or dialectical behavior therapy (DBT).

While deep depression can be a serious and debilitating condition, it is treatable. With proper treatment, individuals can experience significant improvement in their symptoms and a return to functioning in daily life.


American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.

Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62(6), 593-602. doi:10.1001/archpsyc.62.6.593

National Institute of Mental Health. (2020). Mental health medications. Retrieved from

National Institute of Mental Health. (2020). Psychotherapies. Retrieved from

Scroll to Top