BECKWITH-WIEDEMANN SYNDROME
Introduction and Conceptual Definition of Beckwith-Wiedemann Syndrome Beckwith-Wiedemann Syndrome (BWS) represents a sophisticated and multifaceted overgrowth disorder primarily characterized by a spectrum of physical abnormalities and a heightened susceptibility to specific pediatric malignancies. As a congenital condition, BWS manifests through a complex interplay of genetic alterations and epigenetic modifications that disrupt normal growth regulatory pathways. […]