INTRACRANIAL SELF-STIMULATION
Introduction and Definition of Intracranial Self-Stimulation Intracranial self-stimulation (ICSS) is a fundamental experimental technique employed extensively in behavioral neuroscience and psychopharmacology to investigate the neural substrates underlying reward, motivation, and reinforcement. The core principle of ICSS is the observation that animals, typically rodents, will voluntarily initiate and sustain electrical stimulation delivered directly to specific regions […]