Nondisjunction: Causes and Effects Nondisjunction is a type of chromosomal abnormality in which a pair of chromosomes fail to separate during meiosis, resulting in the production of gametes with an incorrect number of chromosomes (He et al., 2018). This can lead to a variety of genetic disorders in offspring, such as Down syndrome, Turner syndrome, […]
Introduction to Sex-Chromosomal Aberrations Sex-chromosomal aberration, frequently referred to as a sex chromosome aneuploidy, represents a category of genetic disorders characterized by the deviation from the typical complement of sex chromosomes (XX for females, XY for males). This deviation involves either the complete or partial absence of a sex chromosome, the presence of extra sex […]
Introduction and Definition of Turner’s Syndrome Turner’s Syndrome (TS) is a pervasive and complex chromosomal disorder affecting females, characterized by the partial or complete absence of one of the two X chromosomes. This genetic anomaly, most commonly resulting in a 45,X karyotype (monosomy X), affects approximately one in every 2,500 live female births globally. The […]