OVULATORY CYCLE

Introduction

The ovulatory cycle is an essential part of the menstrual cycle in which a female produces eggs and hormones to promote fertility. This cycle is regulated by the hypothalamic-pituitary-ovarian (HPO) axis and the gonadotropin-releasing hormone (GnRH). It is a complex process that involves multiple hormones and organs, and can be disrupted by a variety of factors. This article will discuss the components of the ovulatory cycle, the hormones involved, the role of the HPO axis, and the potential disruptions of the cycle.

Components of the Ovulatory Cycle

The ovulatory cycle is a cyclical process that typically occurs once every 28 days in most women. It consists of three phases: follicular, ovulation, and luteal. During the follicular phase, a woman’s body produces follicle stimulating hormone (FSH) and luteinizing hormone (LH) to stimulate the growth and maturation of an egg in the ovary. During the ovulation phase, the egg is released from the ovary and travels down the fallopian tube. The luteal phase is the time after ovulation, where the corpus luteum produces progesterone, which prepares the uterus for a possible pregnancy.

Hormones Involved

The ovulatory cycle is regulated by multiple hormones, including FSH, LH, estradiol, and progesterone. FSH and LH are produced by the anterior pituitary gland and are responsible for stimulating the growth and maturation of the egg. Estradiol is produced by the developing follicle and is responsible for stimulating the release of LH, which triggers ovulation. Progesterone is produced by the corpus luteum and is responsible for maintaining the uterine lining for potential pregnancy.

Role of the HPO Axis

The hypothalamic-pituitary-ovarian (HPO) axis is responsible for the production and release of hormones involved in the ovulatory cycle. The hypothalamus produces gonadotropin-releasing hormone (GnRH), which stimulates the production of FSH and LH from the anterior pituitary gland. FSH and LH then stimulate the production of estradiol and progesterone from the ovaries.

Potential Disruptions

The ovulatory cycle can be disrupted by a variety of factors, including stress, diet, and certain medications. Stress can lead to an increase in cortisol levels, which can affect the HPO axis and disrupt the production and release of hormones. Changes in diet and certain medications, such as oral contraceptives, can also affect the production and release of hormones and disrupt the ovulatory cycle.

Conclusion

The ovulatory cycle is an important part of the menstrual cycle in which a female produces eggs and hormones to promote fertility. It is regulated by the hypothalamic-pituitary-ovarian (HPO) axis and is composed of three phases: follicular, ovulation, and luteal. Multiple hormones are involved in the cycle, including FSH, LH, estradiol, and progesterone. The cycle can be disrupted by a variety of factors, including stress, diet, and certain medications.

References

Coughlan, A. M., & Rana, S. K. (2014). Gonadotropin-releasing hormone, its receptor, and ovarian response: a review. Reproductive biology and endocrinology, 12(1), 54.

Kashanian, M., Khazaei, M., Shokouhi, S., & Badakhshan, A. (2014). Stress and female reproductive system. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences, 19(2), 166.

Santoro, N., & Crawford, S. L. (2012). The Menstrual Cycle: Physiology, Reproductive Disorders, and Infertility. In UpToDate.

Zerafati-Masouleh, M., & Shahverdi, A. H. (2014). Oral contraception: a review. International journal of preventative medicine, 5(7), 884.

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